Assay Detail
Functional
CHEMBL867904
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Survival of human HEK293 cells after 48 hrs by MTS reduction assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.10 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379713 | — | — | 1 | 5.72 |
| CHEMBL378198 | — | — | 1 | 5.52 |
| CHEMBL379858 | — | — | 1 | 5.30 |
| CHEMBL377981 | — | — | 1 | 5.10 |
| CHEMBL373834 | — | — | 1 | 4.91 |
| CHEMBL212581 | — | — | 1 | 4.84 |
| CHEMBL213077 | — | — | 1 | 4.73 |
| CHEMBL210104 | — | — | 1 | 4.67 |
| CHEMBL211430 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379713 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL378198 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL379858 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL377981 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL373834 | — | IC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL212581 | — | IC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL213077 | — | IC50 | = | 18800.0 | nM | 4.73 |
| CHEMBL210104 | — | IC50 | = | 21400.0 | nM | 4.67 |
| CHEMBL211430 | — | IC50 | > | 30000.0 | nM | - |