Assay Detail
Functional
CHEMBL867965
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Inhibition of fMLP-induced PMN migration
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PMNL |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.95 | 6.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL379761 | — | — | 1 | 6.19 |
| CHEMBL208884 | — | — | 1 | 5.70 |
| CHEMBL208831 | — | — | 1 | - |
| CHEMBL377169 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL379761 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL208884 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL208831 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL377169 | — | IC50 | > | 10000.0 | nM | - |