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Assay Detail

CHEMBL868355

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Functional
Inhibition of West Nile viral Rluc-Neo-Rep in Vero cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type Vero
Confidence 1 — Organism
Curated By Expert

Target

Vero (CHEMBL391)
Type CELL-LINE
Organism Chlorocebus sabaeus

Publication

Identification of compounds with anti-West Nile Virus activity.
Goodell JR, Puig-Basagoiti F, Forshey BM, Shi PY, Ferguson DM.
J Med Chem (2006) 49 : 2127 -2137
PubMed 16539402 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 6 5.69 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL866 MYCOPHENOLIC ACID 4.0 1 7.10
CHEMBL203727 1 5.16
CHEMBL202885 1 4.82
CHEMBL1643 RIBAVIRIN 4.0 1 -
CHEMBL206716 1 -
CHEMBL206537 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL866 MYCOPHENOLIC ACID EC50 = 80.0 nM 7.10
CHEMBL203727 EC50 = 7000.0 nM 5.16
CHEMBL202885 EC50 = 15000.0 nM 4.82
CHEMBL1643 RIBAVIRIN EC50 = 119000.0 nM -
CHEMBL206716 EC50 - -
CHEMBL206537 EC50 - -