Assay Detail
Binding
CHEMBL868498
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Inhibition of kallikrein
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.23 | 4.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL211561 | — | — | 1 | 4.37 |
| CHEMBL536972 | — | — | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL211561 | — | Ki | = | 43000.0 | nM | 4.37 |
| CHEMBL536972 | — | Ki | = | 83000.0 | nM | 4.08 |