Assay Detail
Binding
CHEMBL869278
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.96 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215659 | — | — | 1 | 6.10 |
| CHEMBL211564 | — | — | 1 | 5.92 |
| CHEMBL213380 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215659 | — | Ki | = | 800.0 | nM | 6.10 |
| CHEMBL211564 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL213380 | — | Ki | = | 1400.0 | nM | 5.85 |