Assay Detail
ADMET
CHEMBL869680
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Inhibition of human recombinant CYP2B6
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.62 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207831 | — | — | 1 | 4.68 |
| CHEMBL208528 | — | — | 1 | 4.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207831 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL208528 | — | IC50 | = | 28000.0 | nM | 4.55 |