Assay Detail
Binding
CHEMBL870123
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli MTAN
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (CHEMBL1250346) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli O157:H7 |
Publication
Synthesis of a potent 5'-methylthioadenosine/S-adenosylhomocysteine (MTAN) inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.77 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207655 | — | — | 1 | 8.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207655 | — | Ki | = | 1.7 | nM | 8.77 |