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Assay Detail

CHEMBL870425

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Functional
Activity at delta opioid receptor by MVD assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Delta-type opioid receptor (CHEMBL3222)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.
Petrov RR, Vardanyan RS, Lee YS, Ma SW, Davis P, Begay LJ, Lai JY, Porreca F, Hruby VJ.
Bioorg Med Chem Lett (2006) 16 : 4946 -4950
PubMed 16828552 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.46 7.46
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL214022 1 7.46
CHEMBL216239 CARBOXYFENTANYL 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL214022 IC50 = 34.9 nM 7.46
CHEMBL216239 CARBOXYFENTANYL Inhibition = 1.0 % -