Assay Detail
Functional
CHEMBL870490
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Inhibition of ADP-induced platelet aggregation in human platelet rich plasma
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Metabolism investigation leading to novel drug design 2: orally active prostacyclin mimetics. Part 5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 7.32 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213191 | — | — | 1 | 7.89 |
| CHEMBL378832 | — | — | 1 | 7.85 |
| CHEMBL196779 | — | — | 1 | 7.75 |
| CHEMBL213990 | — | — | 1 | 7.66 |
| CHEMBL214068 | — | — | 1 | 7.60 |
| CHEMBL214380 | — | — | 1 | 7.46 |
| CHEMBL213334 | — | — | 1 | 7.31 |
| CHEMBL209599 | — | — | 1 | 7.23 |
| CHEMBL209804 | — | — | 1 | 7.20 |
| CHEMBL213679 | — | — | 1 | 6.70 |
| CHEMBL425916 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213191 | — | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL378832 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL196779 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL213990 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL214068 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL214380 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL213334 | — | IC50 | = | 49.0 | nM | 7.31 |
| CHEMBL209599 | — | IC50 | = | 59.0 | nM | 7.23 |
| CHEMBL209804 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL213679 | — | IC50 | = | 198.0 | nM | 6.70 |
| CHEMBL425916 | — | IC50 | = | 1290.0 | nM | 5.89 |