Assay Detail
Functional
CHEMBL871140
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at mu opioid receptor in longitudinal muscle myenteric plexus from guinea pig ileum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of the first cyclic biphalin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.35 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200199 | BIPHALIN | — | 1 | 8.06 |
| CHEMBL200129 | — | — | 1 | 7.60 |
| CHEMBL372787 | — | — | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200199 | BIPHALIN | IC50 | = | 8.8 | nM | 8.06 |
| CHEMBL200129 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL372787 | — | IC50 | = | 420.0 | nM | 6.38 |