Assay Detail
Binding
CHEMBL871517
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MMP9
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.37 | 4.53 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL213158 | — | — | 1 | 4.53 |
| CHEMBL212723 | — | — | 1 | 4.37 |
| CHEMBL115145 | — | — | 1 | 4.36 |
| CHEMBL438832 | — | — | 1 | 4.22 |
| CHEMBL378575 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL213158 | — | IC50 | = | 29600.0 | nM | 4.53 |
| CHEMBL212723 | — | IC50 | = | 43000.0 | nM | 4.37 |
| CHEMBL115145 | — | IC50 | = | 43400.0 | nM | 4.36 |
| CHEMBL438832 | — | IC50 | = | 60100.0 | nM | 4.22 |
| CHEMBL378575 | — | IC50 | = | 105900.0 | nM | - |