Assay Detail
Binding
CHEMBL871519
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Inhibition of human chymotrypsin
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel small-molecule inhibitors of anthrax lethal factor identified by high-throughput screening.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.10 | 4.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL215448 | — | — | 1 | 4.14 |
| CHEMBL213144 | — | — | 1 | 4.13 |
| CHEMBL383943 | — | — | 1 | 4.04 |
| CHEMBL378575 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL215448 | — | IC50 | = | 72600.0 | nM | 4.14 |
| CHEMBL213144 | — | IC50 | = | 74100.0 | nM | 4.13 |
| CHEMBL383943 | — | IC50 | = | 90300.0 | nM | 4.04 |
| CHEMBL378575 | — | IC50 | = | 143600.0 | nM | - |