Chymotrypsinogen B · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P17538. Use UniProt P17538 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P17538 as the stable identity anchor, then attach disease evidence before program review.
Chymotrypsinogen B
Review this target as Chymotrypsinogen B, mapped to UniProt P17538. Sequence length is 263 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Chymotrypsinogen B as ChEMBL target CHEMBL4796, mapped to UniProt P17538. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Chymotrypsinogen B is the right protein anchor across sources, using UniProt P17538 as the stable mapping.
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| Preferred Name | Chymotrypsinogen B |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P17538 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chymotrypsinogen B |
| UniProt Accession | P17538 |
| Component Type | Protein |
| Sequence Length | 263 aa |
Chymotrypsinogen B
Review this target as Chymotrypsinogen B, mapped to UniProt P17538. Sequence length is 263 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL108540 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL307448 | 8.28 | Ki | 5.3 | Preclinical |
| CHEMBL335675 | 8.28 | IC50 | 5.3 | Preclinical |
| CHEMBL436591 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL134816 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL2409452 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL132171 | 7.77 | Ki | 17.0 | Preclinical |
| CHEMBL134821 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL2409457 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL2409451 | 7.51 | IC50 | 31.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 79 | 98 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 0 | — |