Assay Detail
Functional
CHEMBL871876
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Inhibitory activity (proliferation) against human peripheral blood mononuclear cells stimulated with Phytohemagglutininin-L
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.24 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL193371 | — | — | 1 | 6.00 |
| CHEMBL197194 | VIDOFLUDIMUS | 3.0 | 1 | 4.89 |
| CHEMBL157105 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL193371 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL197194 | VIDOFLUDIMUS | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL157105 | — | IC50 | = | 15000.0 | nM | 4.82 |