Assay Detail
Functional
CHEMBL871946
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Antiviral potency of compound determined against human immunodeficiency virus type 1
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.49 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2062136 | — | — | 1 | 5.82 |
| CHEMBL279580 | — | — | 1 | 5.44 |
| CHEMBL16526 | — | — | 1 | 5.40 |
| CHEMBL16400 | — | — | 1 | 5.30 |
| CHEMBL277138 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2062136 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL279580 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL16526 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL16400 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL277138 | — | IC50 | > | 10000.0 | nM | - |