Assay Detail
Functional
CHEMBL871959
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity of compound was measured on human tumor cell line HL-60.
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.59 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28509 | EDELFOSINE | 2.0 | 1 | 6.00 |
| CHEMBL277939 | — | — | 1 | 5.96 |
| CHEMBL20875 | — | — | 1 | 5.89 |
| CHEMBL1907928 | — | — | 2 | 5.52 |
| CHEMBL277186 | — | — | 1 | 5.52 |
| CHEMBL20974 | — | — | 1 | 4.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28509 | EDELFOSINE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL277939 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL20875 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL1907928 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL277186 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1907928 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL20974 | — | IC50 | = | 12300.0 | nM | 4.91 |