Assay Detail
Functional
CHEMBL872028
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Tested for the inhibitory activity against rat kidney Na+, K+-ATPase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Kidney |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.23 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99704 | — | — | 1 | 6.30 |
| CHEMBL97453 | WEDELOLACTONE | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99704 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL97453 | WEDELOLACTONE | IC50 | = | 700.0 | nM | 6.16 |