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Assay Detail

CHEMBL872033

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against Adenylyl cyclase in rat cortical membranes in the presence of 2''-Me-CCPA at concentration 30 nM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
Franchetti P, Cappellacci L, Marchetti S, Trincavelli L, Martini C, Mazzoni MR, Lucacchini A, Grifantini M.
J Med Chem (1998) 41 : 1708 -1715
PubMed 9572897 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.80 8.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45891 1 8.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45891 IC50 = 1.6 nM 8.80