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Assay Detail

CHEMBL872389

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Cannabinoid receptor 1 (CHEMBL3037)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
Deng H, Gifford AN, Zvonok AM, Cui G, Li X, Fan P, Deschamps JR, Flippen-Anderson JL, Gatley SJ, Makriyannis A.
J Med Chem (2005) 48 : 6386 -6392
PubMed 16190764 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.30 8.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL364266 1 8.89
CHEMBL188 WIN-552122 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL364266 Ki = 1.3 nM 8.89
CHEMBL188 WIN-552122 Ki = 20.0 nM 7.70