Cannabinoid receptor 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P47746. Use UniProt P47746 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P47746 as the stable identity anchor, then attach disease evidence before program review.
Cannabinoid receptor 1
Review this target as Cannabinoid receptor 1, mapped to UniProt P47746. Sequence length is 473 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cannabinoid receptor 1 as ChEMBL target CHEMBL3037, mapped to UniProt P47746. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cannabinoid receptor 1 is the right protein anchor across sources, using UniProt P47746 as the stable mapping.
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| Preferred Name | Cannabinoid receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P47746 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cannabinoid receptor 1 |
| UniProt Accession | P47746 |
| Component Type | Protein |
| Sequence Length | 473 aa |
Cannabinoid receptor 1
Review this target as Cannabinoid receptor 1, mapped to UniProt P47746. Sequence length is 473 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL376700 | 12.46 | Ki | 0.00035 | Preclinical |
| CHEMBL223278 | 12.0 | Ki | 0.001 | Preclinical |
| CHEMBL374933 | 11.4 | Ki | 0.004 | Preclinical |
| CHEMBL224609 | 11.28 | Ki | 0.0052 | Preclinical |
| CHEMBL438782 | 11.1 | Ki | 0.008 | Preclinical |
| CHEMBL387112 | 10.89 | Ki | 0.013 | Preclinical |
| CHEMBL225415 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL364266 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL225622 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL65192 | 9.43 | Ki | 0.37 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 20 | 51 | 7.2 |
| cell membrane format | 16 | 117 | 7.4 |
| assay format | 15 | 18 | 7.1 |
| single protein format | 14 | 27 | 7.4 |
| tissue-based format | 14 | 83 | 7.1 |
| organism-based format | 2 | 87 | 7.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 20 | 13 | 6.0 |
| cell membrane format | 19 | 63 | 7.1 |
| cell-based format | 10 | 8 | 7.7 |
| assay format | 5 | 4 | 6.5 |
| single protein format | 2 | 4 | 6.6 |