Assay Detail
Functional
CHEMBL872693
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration required to inhibit human immunodeficiency virus-1 induced cytopathicity in MT-4 cells by 50%
9
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Polyanion inhibitors of human immunodeficiency virus and other viruses. 6. Micelle-like anti-HIV polyanionic compounds based on a carbohydrate core.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.87 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3215377 | — | — | 1 | 7.40 |
| CHEMBL3142950 | — | — | 1 | 6.75 |
| CHEMBL3217279 | — | — | 1 | 6.43 |
| CHEMBL384019 | — | — | 2 | 6.17 |
| CHEMBL3142960 | — | — | 1 | 4.54 |
| CHEMBL3215375 | — | — | 1 | 4.07 |
| CHEMBL3142956 | — | — | 1 | - |
| CHEMBL3215376 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3215377 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3142950 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL3217279 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL384019 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL384019 | — | IC50 | = | 1850.0 | nM | 5.73 |
| CHEMBL3142960 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL3215375 | — | IC50 | = | 85900.0 | nM | 4.07 |
| CHEMBL3142956 | — | IC50 | > | 127000.0 | nM | - |
| CHEMBL3215376 | — | IC50 | > | 99100.0 | nM | - |