Assay Detail
Binding
CHEMBL873039
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Inhibitory activity against rat adenylate kinase II was determined in the presence of AMP, non competitive inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Adenylate kinase 2, mitochondrial (CHEMBL2376) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Species- or isozyme-specific enzyme inhibitors. 8. Synthesis of disubstituted two-substrate condensation products as inhibitors of rat adenylate kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.55 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL605639 | — | — | 1 | 5.55 |
| CHEMBL605010 | — | — | 1 | - |
| CHEMBL603556 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL605639 | — | Ki | = | 2800.0 | nM | 5.55 |
| CHEMBL605010 | — | Ki | = | 3200000.0 | nM | - |
| CHEMBL603556 | — | Ki | = | 9800000.0 | nM | - |