Assay Detail
Functional
CHEMBL873090
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Inhibition of growth of human keratinocytes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New dermatological agents for the treatment of psoriasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.58 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL318267 | — | — | 1 | 9.96 |
| CHEMBL318617 | — | — | 1 | 9.55 |
| CHEMBL1200666 | CALCIPOTRIENE | 4.0 | 1 | 7.50 |
| CHEMBL846 | CALCITRIOL | 4.0 | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL318267 | — | IC50 | = | 0.11 | nM | 9.96 |
| CHEMBL318617 | — | IC50 | = | 0.28 | nM | 9.55 |
| CHEMBL1200666 | CALCIPOTRIENE | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL846 | CALCITRIOL | IC50 | = | 50.0 | nM | 7.30 |