Assay Detail
Binding
CHEMBL873302
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Inhibition of [3H]- ]DAMGO binding to Opioid receptor mu 1 from rat brain membrane
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Conformationally restricted deltorphin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.53 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL124435 | — | — | 1 | 6.68 |
| CHEMBL124941 | — | — | 1 | 6.17 |
| CHEMBL262312 | — | — | 1 | 5.38 |
| CHEMBL337898 | — | — | 1 | 5.06 |
| CHEMBL339089 | — | — | 1 | 5.04 |
| CHEMBL330991 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL124435 | — | Ki | = | 207.0 | nM | 6.68 |
| CHEMBL124941 | — | Ki | = | 671.0 | nM | 6.17 |
| CHEMBL262312 | — | Ki | = | 4150.0 | nM | 5.38 |
| CHEMBL337898 | — | Ki | = | 8650.0 | nM | 5.06 |
| CHEMBL339089 | — | Ki | = | 9230.0 | nM | 5.04 |
| CHEMBL330991 | — | Ki | = | 15200.0 | nM | 4.82 |