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Assay Detail

CHEMBL873306

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against human oxytocin receptor was determined by using plasma membranes from CHO cells stably transfected with VP/OT receptors
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Oxytocin receptor (CHEMBL2049)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4.
Cheng LL, Stoev S, Manning M, Derick S, Pena A, Mimoun MB, Guillon G.
J Med Chem (2004) 47 : 2375 -2388
PubMed 15084136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.88 6.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2369845 1 6.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2369845 Ki = 131.0 nM 6.88