Assay Detail
Functional
CHEMBL873370
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In vitro inhibitory activity against HIV-1 in MT-4 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-based, C2 symmetric inhibitors of HIV protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 10.24 | 10.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL314298 | — | — | 1 | 10.80 |
| CHEMBL83462 | — | — | 1 | 10.10 |
| CHEMBL314758 | — | — | 1 | 9.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL314298 | — | IC50 | = | 0.016 | nM | 10.80 |
| CHEMBL83462 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL314758 | — | IC50 | = | 0.15 | nM | 9.82 |