Assay Detail
Functional
CHEMBL873504
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Human enterovirus 71 strain 4643 using plaque reduction assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.55 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL194616 | — | — | 1 | 8.05 |
| CHEMBL372209 | — | — | 1 | 7.48 |
| CHEMBL192920 | — | — | 1 | 7.40 |
| CHEMBL45426 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL194616 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL372209 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL192920 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL45426 | — | IC50 | = | 54.0 | nM | 7.27 |