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Assay Detail

CHEMBL873857

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Functional
Inhibitory concentration on L929 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L929
Confidence 1 — Organism
Curated By Intermediate

Target

L929 (CHEMBL612267)
Type CELL-LINE
Organism Mus musculus

Publication

Antiviral enantiomeric preference for 5'-noraristeromycin.
Siddiqi SM, Chen X, Schneller SW, Ikeda S, Snoeck R, Andrei G, Balzarini J, De Clercq E.
J Med Chem (1994) 37 : 551 -554
PubMed 8120872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.34 8.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8771 NEOPLANOCIN A 1 8.28
CHEMBL129014 NORARISTEROMYCIN 1 7.50
CHEMBL2051948 1 6.23

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8771 NEOPLANOCIN A IC50 = 5.2 nM 8.28
CHEMBL129014 NORARISTEROMYCIN IC50 = 32.0 nM 7.50
CHEMBL2051948 IC50 = 590.0 nM 6.23