Assay Detail
Functional
CHEMBL873888
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Evaluated for growth inhibition of UV-4 cells under aerobic or hypoxic conditions
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | UV4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.88 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19868 | — | — | 1 | 6.18 |
| CHEMBL538221 | — | — | 1 | 6.00 |
| CHEMBL281788 | — | — | 1 | 5.82 |
| CHEMBL19995 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19868 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL538221 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL281788 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL19995 | — | IC50 | = | 3200.0 | nM | 5.50 |