Assay Detail
Binding
CHEMBL873993
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity of compound toward bovine trypsin was evaluated
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.16 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110419 | — | — | 1 | 7.16 |
| CHEMBL351298 | — | — | 1 | - |
| CHEMBL48813 | — | — | 1 | - |
| CHEMBL157813 | — | — | 1 | - |
| CHEMBL423417 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110419 | — | Ki | = | 69.0 | nM | 7.16 |
| CHEMBL351298 | — | Ki | > | 2900.0 | nM | - |
| CHEMBL48813 | — | Ki | > | 2900.0 | nM | - |
| CHEMBL157813 | — | Ki | > | 2900.0 | nM | - |
| CHEMBL423417 | — | Ki | > | 2900.0 | nM | - |