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Assay Detail

CHEMBL874088

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Binding
Binding affinity towards rat liver V1a receptor was determined using [3H]arginine vasopressin as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Vasopressin V1a receptor (CHEMBL2868)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product.
Williams PD, Bock MG, Tung RD, Garsky VM, Perlow DS, Erb JM, Lundell GF, Gould NP, Whitter WL, Hoffman JB.
J Med Chem (1992) 35 : 3905 -3918
PubMed 1331448 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.43 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL127686 1 6.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL127686 Ki = 370.0 nM 6.43