Assay Detail
Functional
CHEMBL874210
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration that inhibits 50% of the growth of LCC6/P9 human breast cell carcinoma cell line after 72 hr of drug exposure.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Breast carcinoma cell |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.82 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL364622 | — | — | 1 | 9.00 |
| CHEMBL414281 | — | — | 1 | 8.80 |
| CHEMBL433958 | — | — | 1 | 8.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL364622 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL414281 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL433958 | — | IC50 | = | 2.2 | nM | 8.66 |