Assay Detail
Functional
CHEMBL874635
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Compound was tested for inhibitory activity against HIV in human peripheral blood mononuclear (PBM, LAV strain of HIV-l) cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HIV-l |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiviral optically pure dioxolane purine nucleosides analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.91 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL417332 | — | — | 1 | 7.52 |
| CHEMBL38860 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL417332 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL38860 | — | IC50 | = | 500.0 | nM | 6.30 |