Assay Detail
ADMET
CHEMBL874884
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human LoVo cancer cell line was determined after 144 hr
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | LoVo |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.51 | 9.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL185043 | — | — | 1 | 9.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL185043 | — | IC50 | = | 0.31 | nM | 9.51 |