Assay Detail
Functional
CHEMBL875072
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was evaluated for the antagonistic activity against beta-2 adrenergic receptor.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Indole-phenol bioisosterism. Synthesis and antihypertensive activity of a pyrrolo analogue of labetalol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429 | LABETALOL | 4.0 | 1 | 7.40 |
| CHEMBL7067 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429 | LABETALOL | Kd | = | 39.81 | nM | 7.40 |
| CHEMBL7067 | — | Kd | > | 10000.0 | nM | - |