Assay Detail
Binding
CHEMBL875198
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Binding affinity against rat 5-HT7R expressed in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.46 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL181874 | — | — | 1 | 7.72 |
| CHEMBL177064 | — | — | 1 | 7.68 |
| CHEMBL366516 | — | — | 1 | 6.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL181874 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL177064 | — | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL366516 | — | Ki | = | 105.0 | nM | 6.98 |