Assay Detail
Binding
CHEMBL875201
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Inhibition of human phosphodiesterase 7
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.81 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL932 | DIPYRIDAMOLE | 4.0 | 1 | 6.22 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL932 | DIPYRIDAMOLE | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | Ki | = | 4000.0 | nM | 5.40 |