Assay Detail
Binding
CHEMBL875263
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Binding affinity for adenosine A2 receptor using [3H]NECA in rat striatal membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Striatum |
| Subcellular | Membrane |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
1H-imidazo[4,5-c]quinolin-4-amines: novel non-xanthine adenosine antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.42 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19191 | — | — | 1 | 5.85 |
| CHEMBL19533 | — | — | 1 | 4.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19191 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL19533 | — | Ki | = | 10500.0 | nM | 4.98 |