Assay Detail
Functional
CHEMBL877195
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In vitro inhibition of HL-60 human promyelocytic leukemia cell proliferation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Imidazole and triazole substituted ether phospholipids: potent antitumor agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.64 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL421316 | — | — | 1 | 5.70 |
| CHEMBL28509 | EDELFOSINE | 2.0 | 1 | 5.70 |
| CHEMBL78978 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL421316 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL28509 | EDELFOSINE | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL78978 | — | IC50 | = | 3000.0 | nM | 5.52 |