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Assay Detail

CHEMBL877814

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Binding
Binding affinity towards factor Xa
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Coagulation factor X (CHEMBL244)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors.
Huang W, Zhang P, Zuckett JF, Wang L, Woolfrey J, Song Y, Jia ZJ, Clizbe LA, Su T, Tran K, Huang B, Wong P, Sinha U, Park G, Reed A, Malinowski J, Hollenbach SJ, Scarborough RM, Zhu BY.
Bioorg Med Chem Lett (2003) 13 : 561 -566
PubMed 12565972 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.11 9.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL153640 1 9.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL153640 Ki = 0.78 nM 9.11