Assay Detail
Binding
CHEMBL877988
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Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in mouse vas deferens
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Antinociceptive (aminoalkyl)indoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.77 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12566 | — | — | 1 | 6.24 |
| CHEMBL273606 | — | — | 1 | 5.30 |
| CHEMBL13178 | PRAVADOLINE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12566 | — | IC50 | = | 570.0 | nM | 6.24 |
| CHEMBL273606 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL13178 | PRAVADOLINE | IC50 | > | 30000.0 | nM | - |