Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL878020

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist potency in rat isolated esophageal tunica muscularis mucose.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis of 2-piperazinylbenzothiazole and 2-piperazinylbenzoxazole derivatives with 5-HT3 antagonist and 5-HT4 agonist properties.
Monge A, Peña MC, Palop JA, Calderó JM, Roca J, García E, Romero G, del Río J, Lasheras B.
J Med Chem (1994) 37 : 1320 -1325
PubMed 8176710 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.58 6.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24909 1 6.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24909 EC50 = 263.03 nM 6.58