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Assay Detail

CHEMBL878182

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the competitive antagonism of NKA-stimulated PI (phosphatidylinositol) turnover in hamster urinary bladder tissue using [3H]inositol as radioligand
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Confidence 1 — Organism
Curated By Intermediate

Target

Cricetinae gen. sp. (CHEMBL612361)
Type ORGANISM
Organism Cricetinae gen. sp.

Publication

A new class of high affinity ligands for the neurokinin A NK2 receptor: psi (CH2NR) reduced peptide bond analogues of neurokinin A4-10.
Harbeson SL, Shatzer SA, Le TB, Buck SH.
J Med Chem (1992) 35 : 3949 -3955
PubMed 1331450 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL341015 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL341015 Kd = 199.53 nM 6.70