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Target Snapshot

CHEMBL612361 Target Snapshot

Cricetinae gen. sp. · ORGANISM · Cricetinae gen. sp.

Back to Search Search this target Browse approvals Evidence Card
1,261Compounds
935Assays
2Approved Drugs
20.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cricetinae gen. sp. as ChEMBL target CHEMBL612361. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cricetinae gen. sp.
ORGANISM · Cricetinae gen. sp.
As of 2026-09-14
ChEMBL target ID
CHEMBL612361
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cricetinae gen. sp. still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameCricetinae gen. sp.
Target TypeORGANISM
OrganismCricetinae gen. sp.
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCricetinae gen. sp.
UniProt AccessionN/A

Cricetinae gen. sp.

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Cricetinae gen. sp..

Review nameCricetinae gen. sp.
OrganismCricetinae gen. sp.
Clinical Profile

Clinical Phase Distribution

2
Approved
Assay Mix

Activity Type Distribution

IC5018.0
EC501.0
KD1.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL13470 7.3 IC50 50.12 Preclinical
CHEMBL437797 7.3 EC50 50.0 Preclinical
CHEMBL57765 7.0 IC50 100.0 Preclinical
CHEMBL341015 6.7 Kd 199.53 Preclinical
CHEMBL431135 6.17 IC50 680.0 Preclinical
CHEMBL417769 6.06 IC50 880.0 Preclinical
CHEMBL23 6.01 IC50 980.0 Approved
CHEMBL286053 5.9 IC50 1258.93 Preclinical
CHEMBL53449 5.79 IC50 1620.0 Preclinical
CHEMBL111670 5.61 IC50 2460.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
4
5.5
3
6.0
1
6.5
3
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

DILTIAZEM
CHEMBL23
Approved 1982
Properties Compare Identifier
Assay Landscape

Assay Landscape

936
Total Assays
18
Tested Compounds
1
Assay Types
Functional — 936 assays, 18 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 936 18 5.8

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine