Compound Detail
CHEMBL111670
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Basic Information
| ChEMBL ID | CHEMBL111670 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NZHUXMZTSSZXSB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
372.5
MW (Da)
2.80
ALogP
5
HBA
1
HBD
53.0
PSA (Ų)
0.87
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.61
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cricetinae gen. sp. CHEMBL612361 | IC50 | 5.61 | 5.61 | 2460.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cricetinae gen. sp. | IC50 | = | 2460.0 | nM | 5.61 | Concentration (10 e-6 M) required to block [Ca2+]-induced contraction of K+-depo... | 1507210 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1507210 | 10.1021/jm00095a022 | Cricetinae gen. sp. | 1 |
Data from ChEMBL 36 via Core Engine