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Assay Detail

CHEMBL878322

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Functional
Tested in vitro for histamine H3 receptor mediate inhibition of neurogenic contractions in guinea pig isolated ileum assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Histamine H3 receptor (CHEMBL5076)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Structure-activity relationships of non-imidazole H(3) receptor ligands. Part 2: binding preference for D-amino acids motifs.
Faghih R, Dwight W, Black L, Liu H, Gentles R, Phelan K, Esbenshade TA, Ireland L, Miller TR, Kang CH, Krueger KM, Fox GB, Hancock AA, Bennani YL.
Bioorg Med Chem Lett (2002) 12 : 2035 -2037
PubMed 12113836 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.98 6.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL302196 1 6.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL302196 Kd = 104.71 nM 6.98