Assay Detail
Binding
CHEMBL878743
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The compound was evaluated in vitro for the thrombin inhibition.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and testing of amino-bicycloaryl based orally bioavailable thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.22 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51173 | — | — | 1 | 8.22 |
| CHEMBL97597 | — | — | 1 | 8.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51173 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL97597 | — | Ki | = | 6.2 | nM | 8.21 |