Assay Detail
Binding
CHEMBL879096
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The compound was evaluated for inhibitory activity against Trypsin
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Bisbenzamidine isoxazoline derivatives as factor Xa inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.36 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93445 | — | — | 1 | 6.64 |
| CHEMBL96879 | — | — | 1 | 6.38 |
| CHEMBL92988 | — | — | 1 | 6.32 |
| CHEMBL317590 | — | — | 1 | 6.29 |
| CHEMBL93657 | — | — | 1 | 6.16 |
| CHEMBL433351 | — | — | 1 | - |
| CHEMBL94563 | — | — | 1 | - |
| CHEMBL94761 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93445 | — | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL96879 | — | Ki | = | 420.0 | nM | 6.38 |
| CHEMBL92988 | — | Ki | = | 480.0 | nM | 6.32 |
| CHEMBL317590 | — | Ki | = | 510.0 | nM | 6.29 |
| CHEMBL93657 | — | Ki | = | 700.0 | nM | 6.16 |
| CHEMBL433351 | — | Ki | > | 1200.0 | nM | - |
| CHEMBL94563 | — | Ki | > | 1200.0 | nM | - |
| CHEMBL94761 | — | Ki | > | 1200.0 | nM | - |