Compound Detail
CHEMBL433351
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL433351 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JVAFCPQRCIPPMG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
408.4
MW (Da)
1.23
ALogP
6
HBA
6
HBD
187.7
PSA (Ų)
0.29
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Coagulation factor X CHEMBL244 | Ki | 6.84 | 6.84 | 143.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Coagulation factor X | Ki | = | 143.0 | nM | 6.84 | Inhibition of Factor Xa | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)10081-6 | Coagulation factor X | 1 |
| - | 10.1016/S0960-894X(97)10081-6 | Prothrombin | 1 |
| - | 10.1016/S0960-894X(97)10081-6 | Serine protease 1 | 1 |
Data from ChEMBL 36 via Core Engine