Assay Detail
Functional
CHEMBL879437
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Tested for the inhibition of KB cell growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis, antiproliferative, and antiviral activity of 4-amino-1-(beta-D-ribofuranosyl)pyrrolo[2,3-d]pyridazin-7(6H)-one and related derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.39 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL609505 | — | — | 1 | 5.92 |
| CHEMBL62099 | — | — | 1 | 5.52 |
| CHEMBL611857 | — | — | 1 | 5.21 |
| CHEMBL611541 | — | — | 1 | 4.92 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
| CHEMBL2093055 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL609505 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL62099 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL611857 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL611541 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL182 | GANCICLOVIR | IC50 | > | 100000.0 | nM | - |
| CHEMBL2093055 | — | IC50 | < | 1200.0 | nM | - |